It's up to the player how much time they want to spend on Ancestors: The Humankind Odyssey. To avoid messing up endgame information, the only goal is to get your monkeys to the point where they evolve into humans.
However, if you were trying to scale and reach the end in a reasonable amount of time, it would take around 40-50 hours. The game takes place over eight million years and players can decide how fast time passes. The rest can last a night or a generation, so a lot depends on the player.
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There's also the fact that it's sort of a roguelike game. When all clan members die, the player must start over. Dying would be part of a single-player gaming session rather than the aforementioned forty to fifty hours.
We recommend using a controller since that's how the game was designed and you have plenty of time. There can be a lot of time between game sessions, so be prepared to spend at least 10 minutes per game session.
Here at Tipsforallgames we have guides to Valheim and the Medieval Dynasty for you if you like games that require survival skills and living on your own merits.